黄天文，博士，研究员，获广东省“珠江计划青年拔尖人才”，深圳市“国家级领军人才”称号，中科院“百人计划”及“国家重点人才引进工程青年项目”候选者。2005年本科毕业于南京大学，2012年于中国科学院神经科学研究所获得博士学位后，赴哈佛医学院神经生物学系/Dana-Farber癌症研究所马秋富教授实验室进行博士后训练。黄天文博士运用双门控遗传工具小鼠，建立多个贴近临床的新型疼痛动物模型，探索疼痛引发躯体感觉与负性情绪的神经环路机制，发现了特异性传导持续性疼痛的脊髓神经元类型。2019年加入中科院深圳先进技术研究院脑所和深港脑科学创新研究院，以开发非成瘾性镇痛方法为长期目标，继续深入研究疼痛的神经环路机制。参加科研工作以来，共发表SCI论文15篇，第一/共同第一作者5篇，文章发表在Nature、Nature Neuroscience、Neuron和Journal of Neuroscience等著名期刊上

躯体感觉系统与躯体稳态平衡

1.Ke, J., Lu, W. C., Jing, H. Y., Qian, S., Moon, S. W., Cui, G. F., Qian, W. X., Che, X. J., Zhang, Q., Lai, S. S., Zhang, L., Zhu, Y. J., Xie, J. D., & Huang, T. W. (2024). Functional dissection of parabrachial substrates in processing nociceptive information. Zoological research, 45(3), 633–647.

2.Zhang, Q., Ke, J., Cui, G., Qian, S., Qian, W., Moon, S. W., Sun, Y., Huang, T., & Qin, Z. (2025). The neural ensembles activated by propofol and isoflurane anesthesia across the whole mouse brain. Neuroscience letters, 846, 138080.

3.Yin, G., Duan, K., Dong, D., Du, F., Guo, C., Zhang, C., Liu, X., Sun, Y., Huang, T., Cui, G., & Cheng, L. (2024). Central control of opioid-induced mechanical hypersensitivity and tolerance in mice. Neuron, 112(23), 3897–3923.e10.

4.Huo, J., Du, F., Duan, K., Yin, G., Liu, X., Ma, Q., Dong, D., Sun, M., Hao, M., Su, D., Huang, T., Ke, J., Lai, S., Zhang, Z., Guo, C., Sun, Y., & Cheng, L. (2023). Identification of brain-to-spinal circuits controlling the laterality and duration of mechanical allodynia in mice. Cell reports, 42(4), 112300.

5. Yu, Huan, Huang, Tianwen, Lu, William Weijia, Tong, Liping, Chen, Di. Osteoarthritis Pain. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022,

6.Zhang, Y., Ke, J., Zhou, Y., Liu, X., Huang, T., & Wang, F. (2022). Sex-specific characteristics of cells expressing the cannabinoid 1 receptor in the dorsal horn of the lumbar spinal cord. The Journal of comparative neurology, 530(14), 2451–2473.

7.Sara McEwan, Hyokjoon Kwon, Azeddine Tahiri, Nivetha Shanmugarajah, Weikang Cai, Jin Ke, Tianwen Huang, Ariana Belton, Bhagat Singh, Le Wang, Zhiping P Pang, Ercument Dirice, Esteban A Engel, Abdelfattah El Ouaamari. Deconstructing the origins of sexual dimorphism in sensory modulation of pancreatic β cells. MOLECULAR METABOLISM[J]. 2021

8.Du, H., Lv, H., Xu, Z., Zhao, S., Huang, T., Manyande, A., & Xiong, S. (2020). The mechanism for improving the flesh quality of grass carp (Ctenopharyngodon idella) following the micro-flowing water treatment using a UPLC-QTOF/MS based metabolomics method. Food chemistry, 327, 126777.

9.Huang, T., Lin, S. H., Malewicz, N. M., Zhang, Y., Zhang, Y., Goulding, M., LaMotte, R. H., & Ma, Q. (2019). Identifying the pathways required for coping behaviours associated with sustained pain. Nature, 565(7737), 86–90.

10.Pan, H., Fatima, M., Li, A., Lee, H., Cai, W., Horwitz, L., Hor, C. C., Zaher, N., Cin, M., Slade, H., Huang, T., Xu, X. Z. S., & Duan, B. (2019). Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch. Neuron, 103(6), 1135–1149.e6.

获广东省“珠江计划青年拔尖人才”，深圳市“国家级领军人才”称号，中科院“百人计划”及“国家重点人才引进工程青年项目”候选者。代表性成果累计发表SCI论文10余篇，授权专利8项，其中1项专利已实现产业转化。主持国家自然科学基金区域联合重点项目、国家重点研发计划项目、科技部基础科研项目等8项国家地方项目。培养博士毕业生（含联合培养）2名，硕士毕业生（含联合培养）1名。